psychotherapy
  • Home
  • Mental Health A-Z
    • Community Psychology
      • Cultural Psychology
        • Addiction
          • Abnormal Psychology
        • ADHD, Adult
    • ADHD, Childhood
      • Alcohol Use
    • Anorexia
    • Anxiety
    • APA Format
    • Behavioral Psychology
    • Binge Drinking
    • Binge Eating
    • Biological Psychology
    • Biopsychology
    • Bipolar Disorder
    • Brain Health
    • Caffeine Addiction
    • Cannabis Use
    • Child Development
    • Classical Conditioning
    • Clinical Psychology
    • Cognitive Behavioral Therapy
    • Cognitive Development
    • Cognitive Psychology
    • Color Psychology
    • Counseling Psychology
    • Cross-Cultural Psychology
    • Depression
    • Depression, Childhood
    • Development Psychology
    • Dreaming
    • Drug Use
    • DSM-5 E
    • Eating Disorders
    • Educational Psychology
    • Emotional Abuse
    • Agoraphobia
    • Antisocial Personality Disorder(APD)
    • Avoidant Personality Disorder(AVPD)
    • Borderline Personality Disorder
    • Borderline Personality Disorder(BPD)
    • Dependent Personality Disorder(DPD)
    • Brain Health
    • Debates in Psychology
    • Emotions
    • Experimental Psychology
    • Extroversion
    • Forensic Psychology
    • Generalized Anxiety Disorder
    • Goal Setting
    • Grief & Loss
    • Happiness
    • Health Psychology
    • Healthy Aging
    • Hierarchy of Needs
    • Holistic Health
    • Household Stress
    • Inspiration
    • Intelligence
    • Introversion
    • IQ Scores
    • Job Stress
    • Kleptomania
    • Learning Styles
    • LGBTQ
    • Loneliness
    • Mania and Hypomania
    • Marital Issues
    • Meditation
    • Memory
    • Mental Exercises
    • Mental Health Technology
    • Mindfulness
    • Mood Disorders
    • Motivation
    • Narcissistic Personality Disorder(NPD)
    • personality disorder
    • Psychoanalysis
    • Psychology
    • Self-Improvement
    • Relationships
    • Nature vs. Nurture
    • Nicotine Use
    • Nonverbal Communication
    • Obsessive-Compulsive Disorder
    • Online Therapy
    • Operant Conditioning
    • Opioid Use
    • Panic Disorder
    • Parenting Styles
    • Passive Aggression
    • Personal Growth
    • Personality Disorders
    • Personality Psychology
    • Personality Types
    • Phobias
    • Positive Psychology
    • Psychoanalysis
    • Psychologist Biographies
    • Psychology 101
    • Psychology Careers
    • Psychology Theories
    • Psychosexual Development
    • Psychosocial Development
    • Psychosocial Psychology
    • Psychotherapy
    • PTSD
    • Quit Smoking
    • Race and Identity
    • Recovery
    • Relationship Stress
    • Relationships
    • Schizophrenia
    • School Psychology
    • Self-Improvement
    • Obsessive-Compulsive Personality Disorder(OCD)
    • Paranoid Personality Disorder(PPD)
    • Schizoid Personality Disorder
    • Schizotypal Personality Disorder(SPD)
    • Selective mutism (SM)
    • Separation anxiety disorder
    • Sex Addiction
    • Sexuality
    • Shopping Addiction
    • Situational Stress
    • Sleep
    • Social Anxiety Disorder
    • Social Learning Theory
    • Social Psychology
    • Spirituality
    • Sports Psychology
    • Stress Management
    • Student Resources
    • Study Guides
    • Suicide
    • Technology Addiction
    • Therapy Types
    • Violence and Abuse
    • Workplace Bullying
    • Specific phobias
    • Sports
    • Stress Management
    • Theories
    • therapy
    • VIEW ALL
  • About Us
  • Contact
No Result
View All Result
  • Login
  • Home
  • Mental Health A-Z
    • Community Psychology
      • Cultural Psychology
        • Addiction
          • Abnormal Psychology
        • ADHD, Adult
    • ADHD, Childhood
      • Alcohol Use
    • Anorexia
    • Anxiety
    • APA Format
    • Behavioral Psychology
    • Binge Drinking
    • Binge Eating
    • Biological Psychology
    • Biopsychology
    • Bipolar Disorder
    • Brain Health
    • Caffeine Addiction
    • Cannabis Use
    • Child Development
    • Classical Conditioning
    • Clinical Psychology
    • Cognitive Behavioral Therapy
    • Cognitive Development
    • Cognitive Psychology
    • Color Psychology
    • Counseling Psychology
    • Cross-Cultural Psychology
    • Depression
    • Depression, Childhood
    • Development Psychology
    • Dreaming
    • Drug Use
    • DSM-5 E
    • Eating Disorders
    • Educational Psychology
    • Emotional Abuse
    • Agoraphobia
    • Antisocial Personality Disorder(APD)
    • Avoidant Personality Disorder(AVPD)
    • Borderline Personality Disorder
    • Borderline Personality Disorder(BPD)
    • Dependent Personality Disorder(DPD)
    • Brain Health
    • Debates in Psychology
    • Emotions
    • Experimental Psychology
    • Extroversion
    • Forensic Psychology
    • Generalized Anxiety Disorder
    • Goal Setting
    • Grief & Loss
    • Happiness
    • Health Psychology
    • Healthy Aging
    • Hierarchy of Needs
    • Holistic Health
    • Household Stress
    • Inspiration
    • Intelligence
    • Introversion
    • IQ Scores
    • Job Stress
    • Kleptomania
    • Learning Styles
    • LGBTQ
    • Loneliness
    • Mania and Hypomania
    • Marital Issues
    • Meditation
    • Memory
    • Mental Exercises
    • Mental Health Technology
    • Mindfulness
    • Mood Disorders
    • Motivation
    • Narcissistic Personality Disorder(NPD)
    • personality disorder
    • Psychoanalysis
    • Psychology
    • Self-Improvement
    • Relationships
    • Nature vs. Nurture
    • Nicotine Use
    • Nonverbal Communication
    • Obsessive-Compulsive Disorder
    • Online Therapy
    • Operant Conditioning
    • Opioid Use
    • Panic Disorder
    • Parenting Styles
    • Passive Aggression
    • Personal Growth
    • Personality Disorders
    • Personality Psychology
    • Personality Types
    • Phobias
    • Positive Psychology
    • Psychoanalysis
    • Psychologist Biographies
    • Psychology 101
    • Psychology Careers
    • Psychology Theories
    • Psychosexual Development
    • Psychosocial Development
    • Psychosocial Psychology
    • Psychotherapy
    • PTSD
    • Quit Smoking
    • Race and Identity
    • Recovery
    • Relationship Stress
    • Relationships
    • Schizophrenia
    • School Psychology
    • Self-Improvement
    • Obsessive-Compulsive Personality Disorder(OCD)
    • Paranoid Personality Disorder(PPD)
    • Schizoid Personality Disorder
    • Schizotypal Personality Disorder(SPD)
    • Selective mutism (SM)
    • Separation anxiety disorder
    • Sex Addiction
    • Sexuality
    • Shopping Addiction
    • Situational Stress
    • Sleep
    • Social Anxiety Disorder
    • Social Learning Theory
    • Social Psychology
    • Spirituality
    • Sports Psychology
    • Stress Management
    • Student Resources
    • Study Guides
    • Suicide
    • Technology Addiction
    • Therapy Types
    • Violence and Abuse
    • Workplace Bullying
    • Specific phobias
    • Sports
    • Stress Management
    • Theories
    • therapy
    • VIEW ALL
  • About Us
  • Contact
No Result
View All Result
psychotherapy
No Result
View All Result
Home Uncategorized

Exploring Psychosomatic Inflammation: How Perception and Memory Can Influence Illness

Mozhgan Jamshidi Eyni by Mozhgan Jamshidi Eyni
in Uncategorized
Exploring Psychosomatic Inflammation: How Perception and Memory Can Influence Illness

Psychosomatic disorders are described as diseases emerging with no apparent biological cause, and often include a strong emotional component as a trigger.

Summary: A new mouse study sheds light on how neurons in the brain can activate to trigger inflammation based upon encoded memories of prior infections. The findings shed light on how psychosomatic disorders can occur.

Source: Technion

Your phone pings. It’s a notification from your friend, who you just went out for a drink with last night. According to her text, she has just tested positive for COVID-19. You start feeling your throat, you sneak a short cough, and start to feel your body temperature rising. But then you calm down (after receiving your negative COVID results, of course) and realize these feelings were all in your head. But what if this is exactly it—what if there were indeed neurons in the brain that could induce a sensation of illness, or even an actual disease?

Psychosomatic disorders are described as diseases emerging with no apparent biological cause, and often include a strong emotional component as a trigger.

In a study recently published in Cell, Technion scientists explore the brain’s potential to cause diseases on its own. Specifically, they induced inflammation in mice, and then triggered the neurons in the brain that were active during the initial inflammation.

The study was conducted by the research group of Associate Professor Asya Rolls from the Technion Ruth and Bruce Rappaport Faculty of Medicine, led by Tamar Koren, an M.D./Ph.D. student in the lab.

They showed that during colon inflammation, several brain regions exert enhanced neuronal activity, one of which was the insular cortex (insula). The insula is an area in the brain responsible for interoception, that is the sense of the body’s physiological state. This includes hunger, thirst, pain, and heart rate.

The researchers postulated that if report of inflammation in some area of the body is stored somewhere in the brain, this area responsible for interoception would be involved. Armed with this hypothesis, they induced in mice an inflammation in the colon and using genetic manipulation techniques, “captured” groups of neurons in the insular cortex that showed increased activity during the inflammation.

Once the mice were healthy, the researchers triggered these “captured” neurons artificially. Without any outside stimulus other than this triggering of cells in the brain, inflammation re-emerged, in the exact same area where it was before. “Remembering” the inflammation was enough to reactivate it.

If the brain can generate disease, is it possible that it can also turn it off?

In a similar manner, Tamar also demonstrated the opposite effect: in mice with active inflammation, suppressing the neurons that remembered it produced immediate reduction in the inflammation.

Although this was a basic study in mice, and there are multiple challenges in translating the concept to humans, these discoveries open a new therapeutic avenue for treating chronic inflammatory conditions such as Crohn’s disease, psoriasis, and other autoimmune conditions, by attenuating their memory trace in the brain.

“There are evolutionary advantages to such a connection,” said Prof. Rolls in explaining the strange phenomenon whereby the immune system should be activated by memory alone, without an outside trigger.

“The body needs to respond to infection as quickly as possible before the attacking bacteria or viruses can multiply. If certain activity, for example consuming particular foods, has exposed the body to infection and inflammation once, there is an advantage to gearing up for battle when one is about to engage in the same activity again. A shorter response time would allow the body to defeat the infection faster and with less effort. The problem of course is when such an effective mechanism goes out of control and can on its own generate the disease.”

The group’s findings have broad implications for understanding the way the human mind and body affect each other, but also more immediate implications for understanding and treating illness with a psychosomatic element, like irritable bowel syndrome, and even autoimmune diseases and allergies.

Abstract

Insular cortex neurons encode and retrieve specific immune responses

Highlights

  • Neuronal ensembles in the InsCtx are activated during peripheral inflammation
  • Reactivation of these neurons is sufficient to retrieve peripheral inflammation
  • These InsCtx neurons project to autonomic nervous system control sites (DMV, RVLM)
  • Inhibition of the InsCtx alleviates inflammation during DSS-induced colitis

Summary

Increasing evidence indicates that the brain regulates peripheral immunity, yet whether and how the brain represents the state of the immune system remains unclear.

Here, we show that the brain’s insular cortex (InsCtx) stores immune-related information.

Using activity-dependent cell labeling in mice (FosTRAP), we captured neuronal ensembles in the InsCtx that were active under two different inflammatory conditions (dextran sulfate sodium [DSS]-induced colitis and zymosan-induced peritonitis).

Chemogenetic reactivation of these neuronal ensembles was sufficient to broadly retrieve the inflammatory state under which these neurons were captured.

Thus, we show that the brain can store and retrieve specific immune responses, extending the classical concept of immunological memory to neuronal representations of inflammatory information.

About this psychology and neuroscience research news

Author: Press Office
Source: Technion
Contact: Press Office – Technion
Original Research: Closed access.
“Insular cortex neurons encode and retrieve specific immune responses” by Tamar Koren et al. Cell

First Ever Body Maps of Hallucinations Created

First Ever Body Maps of Hallucinations Created

October 27, 2021
Five Key Theories In Psychology

Five Key Theories In Psychology

October 10, 2021
What is brain health and why is it important?

What is brain health and why is it important?

July 1, 2021
Study Examines Attachment to God and Psychological Distress

Study Examines Attachment to God and Psychological Distress

January 6, 2022
COVID-19 Vaccine Hesitancy Linked to Childhood Trauma

COVID-19 Vaccine Hesitancy Linked to Childhood Trauma

February 2, 2022
Gene Expression in Brains of People With Bipolar Disorder

Gene Expression in Brains of People With Bipolar Disorder

March 10, 2022
Bipolar Disorder

Bipolar Disorder

November 21, 2021

Alexithymia & Childhood Trauma: Unraveling The Mysterious Connection

June 8, 2023

Is the Brain Wired Differently in People With Addiction?

February 19, 2023

Hair Samples Show Meditation Training Reduces Long-Term Stress

October 10, 2021

How to Recognize Burnout Symptoms

September 10, 2022

Disliking Music: What’s the Point?

February 24, 2022

Increased Risk of Dementia and Depression in Rheumatoid Arthritis

June 4, 2022

Sleep Disorders

July 12, 2021

Male depression: Understanding the issues

February 15, 2023

Depressive Disorders Can Lead to Changes in Immune Cells

April 9, 2022
psychotherapy

We bring you the best Counseling services around your life quality, be with us and ask for it in live support.

Categories

Kenud Healing Center

  • Healing Center of Kenud , N9 112 , London , Great Britain
  • +447700305907
  • Jamshidi@kenud.com

Recent News

Thyroid Hormones and Blood Sugar Linked to Major Depressive Disorder Severity

Thyroid Hormones and Blood Sugar Linked to Major Depressive Disorder Severity

June 20, 2023
Alterations in Alcohol Consumption Echo Depression Symptom Changes

Alterations in Alcohol Consumption Echo Depression Symptom Changes

June 18, 2023

© 2023 Psychological counseling Services by Dr. Mozhgan Jamshidi Eyni.

No Result
View All Result
  • Home
  • Mental Health A-Z
    • Community Psychology
      • Cultural Psychology
    • ADHD, Childhood
      • Alcohol Use
    • Anorexia
    • Anxiety
    • APA Format
    • Behavioral Psychology
    • Binge Drinking
    • Binge Eating
    • Biological Psychology
    • Biopsychology
    • Bipolar Disorder
    • Brain Health
    • Caffeine Addiction
    • Cannabis Use
    • Child Development
    • Classical Conditioning
    • Clinical Psychology
    • Cognitive Behavioral Therapy
    • Cognitive Development
    • Cognitive Psychology
    • Color Psychology
    • Counseling Psychology
    • Cross-Cultural Psychology
    • Depression
    • Depression, Childhood
    • Development Psychology
    • Dreaming
    • Drug Use
    • DSM-5 E
    • Eating Disorders
    • Educational Psychology
    • Emotional Abuse
    • Agoraphobia
    • Antisocial Personality Disorder(APD)
    • Avoidant Personality Disorder(AVPD)
    • Borderline Personality Disorder
    • Borderline Personality Disorder(BPD)
    • Dependent Personality Disorder(DPD)
    • Brain Health
    • Debates in Psychology
    • Emotions
    • Experimental Psychology
    • Extroversion
    • Forensic Psychology
    • Generalized Anxiety Disorder
    • Goal Setting
    • Grief & Loss
    • Happiness
    • Health Psychology
    • Healthy Aging
    • Hierarchy of Needs
    • Holistic Health
    • Household Stress
    • Inspiration
    • Intelligence
    • Introversion
    • IQ Scores
    • Job Stress
    • Kleptomania
    • Learning Styles
    • LGBTQ
    • Loneliness
    • Mania and Hypomania
    • Marital Issues
    • Meditation
    • Memory
    • Mental Exercises
    • Mental Health Technology
    • Mindfulness
    • Mood Disorders
    • Motivation
    • Narcissistic Personality Disorder(NPD)
    • personality disorder
    • Psychoanalysis
    • Psychology
    • Self-Improvement
    • Relationships
    • Nature vs. Nurture
    • Nicotine Use
    • Nonverbal Communication
    • Obsessive-Compulsive Disorder
    • Online Therapy
    • Operant Conditioning
    • Opioid Use
    • Panic Disorder
    • Parenting Styles
    • Passive Aggression
    • Personal Growth
    • Personality Disorders
    • Personality Psychology
    • Personality Types
    • Phobias
    • Positive Psychology
    • Psychoanalysis
    • Psychologist Biographies
    • Psychology 101
    • Psychology Careers
    • Psychology Theories
    • Psychosexual Development
    • Psychosocial Development
    • Psychosocial Psychology
    • Psychotherapy
    • PTSD
    • Quit Smoking
    • Race and Identity
    • Recovery
    • Relationship Stress
    • Relationships
    • Schizophrenia
    • School Psychology
    • Self-Improvement
    • Obsessive-Compulsive Personality Disorder(OCD)
    • Paranoid Personality Disorder(PPD)
    • Schizoid Personality Disorder
    • Schizotypal Personality Disorder(SPD)
    • Selective mutism (SM)
    • Separation anxiety disorder
    • Sex Addiction
    • Sexuality
    • Shopping Addiction
    • Situational Stress
    • Sleep
    • Social Anxiety Disorder
    • Social Learning Theory
    • Social Psychology
    • Spirituality
    • Sports Psychology
    • Stress Management
    • Student Resources
    • Study Guides
    • Suicide
    • Technology Addiction
    • Therapy Types
    • Violence and Abuse
    • Workplace Bullying
    • Specific phobias
    • Sports
    • Stress Management
    • Theories
    • therapy
    • VIEW ALL
  • About Us
  • Contact

© 2023 Psychological counseling Services by Dr. Mozhgan Jamshidi Eyni.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
-
00:00
00:00

Queue

Update Required Flash plugin
-
00:00
00:00
  • FR